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SCIENTIFIC PUBLICATIONS

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​Proactive esophageal cooling during laser cardiac ablation: A computer modeling study

March 2024, Lasers in Surgery and Medicine 56(4)

DOI: 10.1002/lsm.23774

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Impact of ultra-short pauses between stacked lesions with and without active esophageal cooling

May 2023, Europace 25 (Supplement_1)

DOI: 10.1093/europace/euad122.717

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Proactive esophageal cooling protects against thermal insults during high-power short-duration radiofrequency cardiac ablation

September 2022, International Journal of Hyperthermia 39(1):1202-1212

DOI: 10.1080/02656736.2022.2121860

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Analysis of thermal effects from pulsed field ablation

November 2023, European Heart Journal 44 (Supplement_2)

DOI: 10.1093/eurheartj/ehad655.381

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An analysis of the influence of atrial wall thickness on the protective effects of proactive esophageal cooling during high-power short-duration radiofrequency ablation

October 2022, European Heart Journal 43 (Supplement_2)

DOI: 10.1093/eurheartj/ehac544.468

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Mechanisms of Action Behind the Protective Effects of Proactive Esophageal Cooling During Radiofrequency Catheter Ablation in the Left Atrium

May 2024, Heart Rhythm O2

DOI: 10.1016/j.hroo.2024.05.002

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OUTSTANDING PROJECTS

Radiofrequency

ablation

We obtain temperature profiles and thermal lesion dimensions to analyze the effectiveness and safety of the therapy.

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Pulse field

ablation

We simulate the distribution of temperature, electric field, and electroporated volume to assess the selectivity and safety of the treatment.

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PFA+RFA

We model technologies that combine thermal and non-thermal energy to study their effectiveness, safety thresholds, and esophageal risk.

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Esophageal cooling

We evaluate the effectiveness of a proactive cooling device designed to reduce the risk of esophageal injury during RFA.

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ABLATION

Use advanced simulation to refine ablation parameters, evaluate safety thresholds, and identify risk factors—ensuring precision and safety in ablation treatments.

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KEY FEATURES

Biological and physical phenomena:

Electromagnetism, Heat Transfer, Mechanisms of Cell Death, Fluid Flow.

Types of Ablation Devices and Treatments:

  • RF, PFA, Cryoablation, Laser, microwave.

  • Esophageal protection and monitoring.

In silico results for regulatory compliance (FDA and CE):

  • Temperature profiles.

  • Energy, power, voltage, current, impedance, among others.

Aplicaciones:

  • Cardiac ablation.

  • Tumor ablation.​

  • Others

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